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Anagraine

Metoclopramide hydrochloride / Paracetamol

Consumer Medicine Information (CMI)

What is in this leaflet

This leaflet answers some common questions about Anagraine. It does not contain all the available information. It does not take the place of talking to your pharmacist or doctor.

All medicines have risks and benefits

.

If you have any concerns about taking this medicine, talk to your doctor or pharmacist.

Keep this leaflet with the medicine.

You may need to read it again.

What Anagraine is used for

Anagraine is used for the relief of headache, nausea and vomiting associated with migraine.

Anagraine contains the active ingredients metoclopramide (as metoclopramide hydrochloride anhydrous) and paracetamol.

Metoclopramide helps control nausea and vomiting caused by migraine and other illnesses. It works by blocking the action of a chemical in the brain which causes nausea and vomiting. It also acts in the stomach and upper intestine to increase muscle contractions.

Paracetamol is an analgesic. It provides effective temporary relief from pain.

There is no evidence that Anagraine is addictive.

Before you take it

When you must not take it

Do not take Anagraine if you have ever had an allergic reaction to:

• metoclopramide

• paracetamol

• any of the ingredients listed at the end of this leaflet.

Symptoms of an allergic reaction may include asthma, wheezing, shortness of breath, swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing, skin rash, itching or hives.

Do not take it if you have any of the following conditions:

•

bleeding from the stomach and/or digestive tract

• intestinal blockage

• recent surgery on the stomach and/or digestive tract

• phaeochromocytoma (a rare tumour of the adrenal gland).

Do not take Anagraine if:

• you are pregnant, or intend to become pregnant

It may affect your developing baby if you take it during pregnancy.

•

you are breast-feeding or intend to breast-feed

Anagraine passes into breast milk and therefore may harm the baby.

Do not take Anagraine after the expiry date (EXP) printed on the pack.

Do not take it if the packaging is torn or shows signs of tampering or if the tablets do not look quite right.

Do not give this medicine to children under 12 years of age.

The safety of this medicine in children under 12 years of age has not been established.

Talk to your doctor or pharmacist if you are not sure whether you should start taking Anagraine.

Before you start to take it

Tell your doctor or pharmacist if:

1. you have allergies to any other medicines, foods, preservatives or dyes.

2. you have or have had any of the following medical conditions:

• epilepsy - metoclopramide may increase the risk of you having a fit

• liver or kidney disease

• Parkinson's disease - metoclopramide may make this condition worse.

If you have not told your doctor or pharmacist about any of the above, tell them before you take Anagraine.

Taking other medicines

Tell your doctor or pharmacist if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop.